Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | LTC4S | Q16873 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11323696 | 0.88 | CTSD (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL11320377 | 0.84 | LMNA (0.43) | TP53RAD52SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL11295764 | 0.79 | PPARG (0.43) | PPARGPPARASMN1; SMN2HTTPOLB | |
| SCHEMBL11320533 | 0.79 | TSHR (0.54) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL11320422 | 0.78 | SMN1; SMN2 (0.43) | PPARGPPARASMN1; SMN2ALDH1A1 | |
| SCHEMBL11337953 | 0.77 | KMT2A (0.45) | TSHRALDH1A1HSD17B10POLBHPGD | |
| SCHEMBL11292002 | 0.77 | BACE1 (0.42) | SMN1; SMN2TSHRHTTLMNA | |
| SCHEMBL11291339 | 0.76 | HTT (0.48) | RAD52ALDH1A1HSD17B10HTTLTC4S | |
| SCHEMBL11298142 | 0.76 | SMN1; SMN2 (0.43) | PPARGPPARASMN1; SMN2ALDH1A1 | |
| SCHEMBL11326794 | 0.76 | CNR2 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243678-A | GASTROINTESTINAL DISORDERS, LIVER DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-01-06 | — | — | US | disclosed |