Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 6/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11331398 | 0.91 | CASR (0.55) | CASRADRB2ADRB1SLC6A4SLC6A3 | |
| SCHEMBL11089023 | 0.89 | ADRB2 (0.43) | CASRADRB2ADRB1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL11089050 | 0.88 | ADRB2 (0.42) | CASRADRB2ADRB1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL11328558 | 0.86 | BLM (0.56) | CASRADRB2ADRB1NFKB1SLC6A4 | |
| SCHEMBL11323917 | 0.84 | CASR (0.50) | CASRADRB2ADRB1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL11334604 | 0.83 | CASR (0.52) | CASRADRB2SLC6A4SLC6A3ADRB3 | |
| SCHEMBL11328599 | 0.82 | CASR (0.48) | CASRADRB2ADRB1ALDH1A1ADRB3 | |
| SCHEMBL7337495 | 0.81 | ADRB2 (0.72) | ADRB2ADRB1ALDH1A1LMNANPSR1 | |
| Oxalic Acid SCHEMBL11330847 | 0.80 | MEN1 (0.48) | CASRADRB2ADRB1ALDH1A1ADRB3 | |
| Hydrochloric Acid SCHEMBL7348099 | 0.80 | ADRB2 (0.70) | ADRB2ADRB1ALDH1A1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4276304-A | ANTIDIABETIC, ANTICOAGULANTS | TANABE SEIYAKU CO., LTD. (JP) | 1981-06-30 | — | — | US | claimed |