SCHEMBL11328599

SCHEMBL11328599

COc1ccc(CC(C)(C)NCC(O)c2ccccc2OC(=O)C(=O)O)cc1OC

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CASR P41180 7/20 0.48
ADRB2 P07550 5/20 0.47
ADRB1 P08588 5/20 0.47
ADRB3 P13945 5/20 0.47
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41
CYP2D6 P10635 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11331398 0.88 CASR (0.55) CASRADRB2ADRB1ADRB3CYP2D6
SCHEMBL11335303 0.88 CASR (0.55) CASRADRB2ADRB1ADRB3KDM4E
Oxalic Acid SCHEMBL11330847 0.86 MEN1 (0.48) CASRADRB2ADRB1ADRB3ALDH1A1
SCHEMBL11323917 0.84 CASR (0.50) CASRADRB2ADRB1ADRB3ALDH1A1
SCHEMBL11337562 0.83 KDM4E (0.45) CASRADRB2ADRB1ADRB3ALDH1A1
SCHEMBL11331881 0.83 ADRB1 (0.45) CASRADRB2ADRB1ADRB3ALDH1A1
SCHEMBL11328565 0.82 CASR (0.51) CASRADRB2ADRB1ADRB3ALDH1A1
Hydrochloric Acid SCHEMBL11334604 0.81 CASR (0.52) CASRADRB2ADRB3CYP2D6
SCHEMBL11087921 0.81 ADRB1 (0.52) ADRB2ADRB1ADRB3ALDH1A1KDM4E
Hydrochloric Acid SCHEMBL11328558 0.80 BLM (0.56) CASRADRB2ADRB1ADRB3CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4276304-A ANTIDIABETIC, ANTICOAGULANTS TANABE SEIYAKU CO., LTD. (JP) 1981-06-30 US disclosed