SCHEMBL11323917

SCHEMBL11323917

COc1ccc(CC(C)(C)NCC(O)c2ccccc2OCc2ccccc2)cc1OC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASR P41180 6/20 0.50
KDM4E B2RXH2 3/20 0.46
BCHE P06276 2/20 0.46
LMNA P02545 2/20 0.46
HTT P42858 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
NPY1R P25929 1/20 0.46
NPY2R P49146 1/20 0.46
KMT2A Q03164 1/20 0.46
ADRB2 P07550 2/20 0.46
ABCB1 P08183 1/20 0.46
ABCG2 Q9UNQ0 1/20 0.46
MTNR1A P48039 2/20 0.45
MTNR1B P49286 2/20 0.45
HTR1A P08908 1/20 0.44
ADRA1D P25100 1/20 0.44
ADRA1A P35348 1/20 0.44
ADRA1B P35368 1/20 0.44
F2 P00734 1/20 0.43
F10 P00742 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxalic Acid SCHEMBL11330847 0.96 MEN1 (0.48) CASRKDM4EKMT2AADRB2MTNR1A
Hydrochloric Acid SCHEMBL11331398 0.90 CASR (0.55) CASRADRB2CYP2D6ADRB1ADRB3
Hydrochloric Acid SCHEMBL11080710 0.89 ABCB1 (0.43) KDM4EBCHELMNAHTTSMN1; SMN2
SCHEMBL11325988 0.87 CASR (0.60) CASRLMNAADRB2HTR1AADRA1A
Hydrochloric Acid SCHEMBL11334604 0.87 CASR (0.52) CASRADRB2CYP2D6ADRB3
Hydrochloric Acid SCHEMBL11321482 0.86 CASR (0.59) CASRLMNAADRB2HTR1AADRA1A
SCHEMBL11330850 0.85 MTNR1A (0.46) CASRKDM4EBCHELMNAHTT
SCHEMBL11328599 0.84 CASR (0.48) CASRKDM4EADRB2ALDH1A1CYP2D6
SCHEMBL11331143 0.84 HTR1A (0.42) CASRKDM4EBCHESMN1; SMN2HTR1A
SCHEMBL11328565 0.84 CASR (0.51) CASRLMNAADRB2ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4276304-A ANTIDIABETIC, ANTICOAGULANTS TANABE SEIYAKU CO., LTD. (JP) 1981-06-30 US claimed