Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5711663 | 0.98 | ACHE (0.31) | ACHE | |
| SCHEMBL2489382 | 0.65 | APOBEC3A (0.47) | ACHE | |
| SCHEMBL13567372 | 0.64 | CYP2A6 (0.38) | ACHE | |
| SCHEMBL2489031 | 0.64 | ACHE (0.38) | ACHE | |
| Hydrochloric Acid SCHEMBL6368017 | 0.63 | APOBEC3A (0.45) | ACHE | |
| SCHEMBL9761193 | 0.60 | — | — | |
| SCHEMBL16673246 | 0.60 | APOBEC3A (0.38) | ACHE | |
| SCHEMBL455146 | 0.59 | — | — | |
| SCHEMBL6744912 | 0.59 | ACHE (0.47) | ACHE | |
| SCHEMBL13432835 | 0.59 | APOBEC3A (0.41) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10351620-B2 | Human IgM antibodies, and diagnostic and therapeutic uses thereof particularly in the central nervous system | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2019-07-16 | — | — | US | disclosed |
| US-20180086821-A1 | HUMAN IgM ANTIBODIES, AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF PARTICULARLY IN THE CENTRAL NERVOUS SYSTEM | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2018-03-29 | — | — | US | disclosed |
| US-9701745-B2 | Human IgM antibodies, and diagnostic and therapeutic uses thereof particularly in the central nervous system | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2017-07-11 | — | — | US | disclosed |
| US-20160333078-A1 | HUMAN IgM ANTIBODIES, AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF PARTICULARLY IN THE CENTRAL NERVOUS SYSTEM | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2016-11-17 | — | — | US | disclosed |
| EP-2287191-B1 | HUMAN IGM ANTIBODIES WITH THE CAPABILITY OF INDUCING REMYELINATION, AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF PARTICULARLY IN THE CENTRAL NERVOUS SYSTEM | MAYO FOUNDATION (US) | 2016-10-12 | — | — | EP | disclosed |
| US-9260512-B2 | Human IgM antibodies, and diagnostic and therapeutic uses thereof particularly in the central nervous system | MAYO FOUNDATION FOR MEDICAL EDUCATION & RESEARCH (US) | 2016-02-16 | — | — | US | disclosed |
| EP-2287190-B1 | Human igm antibodies with the capability of inducing remyelination, and diagnostic and therapeutic uses thereof particularly in the central nervous system | MAYO FOUNDATION (US) | 2014-12-17 | — | — | EP | disclosed |
| US-20140065167-A1 | HUMAN IgM ANTIBODIES, AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF PARTICULARLY IN THE CENTRAL NERVOUS SYSTEM | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2014-03-06 | — | — | US | disclosed |
| US-8420795-B2 | Human IgM antibodies, and diagnostic and therapeutic uses thereof particularly in the central nervous system | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2013-04-16 | — | — | US | disclosed |
| WO-2012030455-A3 | SYSTEM AND METHODS FOR BATTERY MANAGEMENT | PROTERRA INC. (US) | 2012-05-10 | — | — | WO | disclosed |
| EP-2287190-A2 | HUMAN IGM ANTIBODIES WITH THE CAPABILITY OF INDUCING REMYELINATION, AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF PARTICULARLY IN THE CENTRAL NERVOUS SYSTEM | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2011-02-23 | — | — | EP | disclosed |
| EP-2287191-A2 | HUMAN IGM ANTIBODIES WITH THE CAPABILITY OF INDUCING REMYELINATION, AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF PARTICULARLY IN THE CENTRAL NERVOUS SYSTEM | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2011-02-23 | — | — | EP | disclosed |
| US-7807166-B2 | Methods of promoting remyelination of central nervous system axons by administrating sHIgM22 | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2010-10-05 | — | — | US | disclosed |
| US-20090274690-A1 | Human IgM antibodies, and diagnostic and therapeutic uses thereof particularly in the central nervous system | MAYO FOUNDATION (US) | 2009-11-05 | — | — | US | disclosed |
| US-7473423-B2 | Human IgM antibodies, and diagnostic and therapeutic uses thereof particularly in the central nervous system | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2009-01-06 | — | — | US | disclosed |
| US-20030185827-A1 | Human IgM antibodies, and diagnostic and therapeutic uses thereof particularly in the central nervous system | MAYO FOUNDATION (US) | 2003-10-02 | — | — | US | disclosed |
| EP-1294770-A1 | HUMAN IGM ANTIBODIES WITH THE CAPABILITY OF INDUCING REMYELINATION, AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF PARTICULARLY IN THE CENTRAL NERVOUS SYSTEM | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001085797-A1 | HUMAN IGM ANTIBODIES WITH THE CAPABILITY OF INDUCING REMYELINATION, AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF PARTICULARLY IN THE CENTRAL NERVOUS SYSTEM | MAYO FOUNDATION FOR MEDICAL EDUCATION & RESEARCH (US) | 2001-11-15 | — | — | WO | disclosed |
| EP-0801679-A1 | MONOCLONAL ANTIBODIES WHICH PROMOTE CENTRAL NERVOUS SYSTEM REMYELINATION | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1997-10-22 | — | — | EP | disclosed |
| WO-1995030004-A1 | MONOCLONAL ANTIBODIES WHICH PROMOTE CENTRAL NERVOUS SYSTEM REMYELINATION | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1995-11-09 | — | — | WO | disclosed |