Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 10/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2489382 | 0.96 | APOBEC3A (0.47) | APOBEC3AAPOBEC3GKDM4EALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL11860221 | 0.82 | ACHE (0.47) | APOBEC3AAPOBEC3GKDM4EALDH1A1TDP1 | |
| SCHEMBL13432835 | 0.80 | APOBEC3A (0.41) | APOBEC3AAPOBEC3GKDM4EALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL12098215 | 0.80 | TSHR (0.45) | APOBEC3AAPOBEC3GKDM4EALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL12098089 | 0.80 | ACHE (0.42) | APOBEC3AAPOBEC3GKDM4EALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL10759629 | 0.80 | CYP3A4 (0.45) | APOBEC3AAPOBEC3GKDM4EALDH1A1TDP1 | |
| SCHEMBL7763343 | 0.78 | ACHE (0.50) | APOBEC3AAPOBEC3GALDH1A1TDP1ACHE | |
| Hydrochloric Acid SCHEMBL146078 | 0.76 | ALDH1A1 (0.46) | KDM4EALDH1A1TDP1LMNATSHR | |
| Hydrochloric Acid SCHEMBL9420749 | 0.76 | ALDH1A1 (0.44) | APOBEC3AAPOBEC3GKDM4EALDH1A1TDP1 | |
| Bromide SCHEMBL8612061 | 0.76 | ACHE (0.47) | APOBEC3AAPOBEC3GALDH1A1TDP1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050131192-A1 | Polymer and process for producing polymer | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2005-06-16 | — | — | US | disclosed |