Glycolic Acid

Glycolic Acid

SCHEMBL11329922

NC1C(N)[C@H]2CC[C@@H]1C2.O=C(O)CO.O=C(O)CO.[Pt]

nearest known ligand 0.38

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC6A12 P48065 3/20 0.38
SLC6A11 P48066 3/20 0.38
SLC6A13 Q9NSD5 3/20 0.38
CYP1A2 P05177 2/20 0.35
MEN1 O00255 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
TSHR P16473 1/20 0.35
KMT2A Q03164 1/20 0.35
NISCH Q9Y2I1 1/20 0.35
GABRR1 P24046 1/20 0.32
HSD11B1 P28845 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycolic Acid SCHEMBL10887541 1.00 SLC6A12 (0.38) SLC6A12SLC6A11SLC6A13CYP1A2MEN1
Chloroacetic Acid SCHEMBL11335198 0.84 TSHR (0.43) SLC6A12SLC6A11SLC6A13CYP1A2MEN1
Oxalic Acid SCHEMBL11330545 0.83 MEN1 (0.39) SLC6A12SLC6A11SLC6A13CYP1A2MEN1
SCHEMBL10890710 0.77 MEN1 (0.50) CYP1A2MEN1CYP3A4CYP2D6TSHR
SCHEMBL10818644 0.77 MEN1 (0.50) CYP1A2MEN1CYP3A4CYP2D6TSHR
SCHEMBL9746214 0.74
SCHEMBL3482710 0.74
Sulfuric Acid SCHEMBL11325182 0.73 MEN1 (0.39) CYP1A2MEN1CYP3A4CYP2D6TSHR
Glycolic Acid SCHEMBL10888599 0.71 THRB (0.50) SLC6A12SLC6A11SLC6A13MEN1CYP2D6
Glycolic Acid SCHEMBL10888921 0.71 THRB (0.50) SLC6A12SLC6A11SLC6A13MEN1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4359425-A OF A DIAMONO FUSED SATURATED HYDROCARBON RING, HAVING ANTITUMOR ACTIVITY SHIONOGI & CO., LTD. (JP) 1982-11-16 US claimed
US-4359425-A OF A DIAMONO FUSED SATURATED HYDROCARBON RING, HAVING ANTITUMOR ACTIVITY SHIONOGI & CO., LTD. (JP) 1982-11-16 US disclosed