Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7503754 | 0.83 | TMEM97 (0.38) | MEN1KMT2ACHRM2CHRM1CHRM3 | |
| SCHEMBL7507128 | 0.82 | HTR2A (0.39) | HTR2ACYP2D6SLC6A2HRH1CYP1A2 | |
| SCHEMBL12124884 | 0.81 | SLC6A2 (0.39) | HTR2ASLC6A2SLC6A3MEN1HRH1 | |
| SCHEMBL12608420 | 0.81 | MAOA (0.36) | HTR2AMEN1HRH1KMT2AKDM4E | |
| SCHEMBL12565935 | 0.80 | SSTR4 (0.37) | HTR2ASLC6A2HRH1KDM4EHTR2C | |
| SCHEMBL10595263 | 0.78 | CYP1A2 (0.41) | HTR2ACYP2D6MEN1HRH1KMT2A | |
| SCHEMBL7503701 | 0.77 | ABCB1 (0.41) | KCNH2 | |
| SCHEMBL803154 | 0.77 | ITGB2 (0.41) | LMNAHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29960516 | 0.72 | KCNH2 (0.44) | HTR2ACYP2D6SLC6A2MEN1TP53 | |
| SCHEMBL7547914 | 0.72 | ALDH1A1 (0.41) | HTR2AMEN1TP53HRH1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2287173-A1 | 10A-AZALIDE COMPOUND HAVING 4-MEMBERED RING STRUCTURE | Taisho Pharmaceutical Co., Ltd. (JP) | 2011-02-23 | — | — | EP | disclosed |