Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 6/20 | 0.38 |
| ▸ | HRH1 | P35367 | 4/20 | 0.38 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.37 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.37 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7507128 | 0.80 | HTR2A (0.39) | CYP1A2CYP2D6HTR2AHRH1HTR2C | |
| SCHEMBL12124884 | 0.79 | SLC6A2 (0.39) | HTR2AHRH1SSTR4HTR2CMEN1 | |
| SCHEMBL12608420 | 0.78 | MAOA (0.36) | HTR2AHRH1SSTR4HTR2CMEN1 | |
| SCHEMBL1132995 | 0.78 | HTR2A (0.37) | CYP1A2CYP2D6HTR2AHRH1SSTR4 | |
| SCHEMBL12565935 | 0.77 | SSTR4 (0.37) | HTR2AHRH1SSTR4HTR2CMAOA | |
| SCHEMBL7503701 | 0.75 | ABCB1 (0.41) | — | |
| SCHEMBL803154 | 0.75 | ITGB2 (0.41) | SMN1; SMN2 | |
| SCHEMBL7503754 | 0.73 | TMEM97 (0.38) | MEN1KMT2AMAOA | |
| SCHEMBL7547914 | 0.70 | ALDH1A1 (0.41) | HTR2AHRH1DRD2MEN1KMT2A | |
| SCHEMBL10595268 | 0.68 | HTR1A (0.44) | HTR2AHRH1DRD2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1146876-A | — | — | None | — | — | JP | disclosed |
| JP-H01146876-A | AMINOALKYLBENZOPYRAN DERIVATIVE | DAI ICHI SEIYAKU CO LTD | 1989-06-08 | — | — | JP | disclosed |