Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TSPO | P30536 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11335080 | 0.85 | HCRTR1 (0.41) | HCRTR1HCRTR2SMN1; SMN2GRM5NPC1 | |
| SCHEMBL11332811 | 0.81 | HPGD (0.43) | HSD17B10HCRTR1HCRTR2GRM5ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11329758 | 0.80 | HPGD (0.43) | HSD17B10HCRTR1HCRTR2GRM5ALDH1A1 | |
| SCHEMBL11327564 | 0.76 | HSD17B10 (0.43) | HSD17B10TSPOSMN1; SMN2NPC1PKM | |
| Iodide SCHEMBL11332677 | 0.76 | HSD17B10 (0.42) | HSD17B10TSPOSMN1; SMN2NPC1PKM | |
| Hydrochloric Acid SCHEMBL11327315 | 0.76 | HSD17B10 (0.42) | HSD17B10TSPOSMN1; SMN2NPC1PKM | |
| SCHEMBL11327274 | 0.75 | RAB9A (0.50) | SMN1; SMN2RAB9AALDH1A1MAPTBRD4 | |
| Iodide SCHEMBL11338064 | 0.74 | RAB9A (0.49) | SMN1; SMN2RAB9AALDH1A1MAPTBRD4 | |
| SCHEMBL12844304 | 0.73 | GRM5 (0.52) | SMN1; SMN2GRM5NPC1RAB9AALDH1A1 | |
| SCHEMBL29133579 | 0.72 | GRM5 (0.51) | SMN1; SMN2GRM5NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE30812-E | ANTIARRHTHMIA AGENTS | MEAD JOHNSON & COMPANY (US) | 1981-12-01 | — | — | US | disclosed |
| US-RE30811-E | SEROTONIN ANTAGONISTS, ANTIARRHYTHMIA AGENTS | MEAD JOHNSON & COMPANY (US) | 1981-12-01 | — | — | US | disclosed |
| US-4064254-A | ANTIARRHYTHMIC AND ANTISEROTONINE AGENTS | MEAD JOHNSON & COMPANY (US) | 1977-12-20 | — | — | US | disclosed |
| US-4000143-A | ANTIARRHYTHMIC AND ANTISEROTONIN AGENTS | MEAD JOHNSON & COMPANY (US) | 1976-12-28 | — | — | US | disclosed |
| US-3931195-A | ANTIARRHYTHMIA, ANTISEROTONIN | MEAD JOHNSON & COMPANY (US) | 1976-01-06 | — | — | US | disclosed |