Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MLYCD | O95822 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12844304 | 0.88 | GRM5 (0.52) | GRM5HPGDALDH1A1MAPTMLYCD | |
| SCHEMBL29024751 | 0.85 | HCAR3 (0.41) | GRM5HPGDMAPTTDP1NPC1 | |
| SCHEMBL5437061 | 0.81 | GRM5 (0.47) | GRM5HPGDALDH1A1MAPTMLYCD | |
| SCHEMBL5434700 | 0.80 | RARB (0.47) | GRM5HPGDALDH1A1MAPTLMNA | |
| SCHEMBL5430899 | 0.80 | HCAR3 (0.54) | GRM5HPGDALDH1A1MAPTMLYCD | |
| SCHEMBL5429605 | 0.79 | GRM5 (0.54) | GRM5HPGDALDH1A1MAPTMLYCD | |
| SCHEMBL998975 | 0.79 | GRM5 (0.54) | GRM5HPGDALDH1A1MAPTMLYCD | |
| SCHEMBL2749675 | 0.78 | KCNJ1 (0.45) | HPGDMAPTLMNANPC1RAB9A | |
| SCHEMBL31098145 | 0.78 | KCNJ1 (0.45) | HPGDMAPTLMNANPC1RAB9A | |
| SCHEMBL5428631 | 0.78 | RAB9A (0.49) | GRM5HPGDALDH1A1MAPTMLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117337289-A | Tetracyclic compounds for the treatment of brain disorders | 加利福尼亚大学董事会 | 2024-01-02 | — | — | CN | disclosed |