SCHEMBL11330804

SCHEMBL11330804

c1ccc2[nH]c(Cc3nc4ccccc4s3)nc2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.59
MAPT P10636 3/20 0.59
HTT P42858 3/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
GAA P10253 3/20 0.57
TSHR P16473 1/20 0.54
POLB P06746 2/20 0.51
DDAH1 O94760 1/20 0.51
UBE2T Q9NPD8 1/20 0.51
ASIC3 Q9UHC3 1/20 0.51
PKM P14618 2/20 0.50
KRAS P01116 1/20 0.48
GRIN1 Q05586 1/20 0.48
GRIN2B Q13224 1/20 0.48
BCHE P06276 1/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
EGFR P00533 1/20 0.47
ERBB2 P04626 1/20 0.47
HKDC1 Q2TB90 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22164295 0.86 PKM (0.48) LMNAMAPTHTTSMN1; SMN2GAA
SCHEMBL3013454 0.82 BCHE (0.61) LMNAMAPTHTTSMN1; SMN2GAA
SCHEMBL3006030 0.82 BCHE (0.61) LMNAMAPTHTTSMN1; SMN2GAA
SCHEMBL7409412 0.81 MAPT (0.48) LMNAMAPTHTTSMN1; SMN2GAA
SCHEMBL7771675 0.80 SMN1; SMN2 (0.52) LMNAMAPTHTTSMN1; SMN2GAA
SCHEMBL7409101 0.80 F10 (0.60)
SCHEMBL226465 0.79 UBE2T (0.70) LMNAMAPTHTTSMN1; SMN2GAA
SCHEMBL230024 0.79 GAA (0.78) LMNAMAPTHTTSMN1; SMN2GAA
SCHEMBL7409406 0.78 F2 (0.44) LMNAMAPTHTTSMN1; SMN2GAA
SCHEMBL10365449 0.78 NPSR1 (0.62) LMNAMAPTHTTSMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115348979-B Methacrylic copolymer, composition, molded body, method for producing film or sheet, and laminate 株式会社可乐丽 2024-10-22 CN disclosed
EP-3581609-B1 ACRYLIC RESIN BIAXIALLY STRETCHED FILM AND METHOD FOR MANUFACTURING THE SAME KURARAY CO (JP) 2023-08-02 EP disclosed
EP-4130058-A1 METHACRYLIC COPOLYMER, COMPOSITION, SHAPED OBJECT, METHOD FOR PRODUCING FILM OR SHEET, AND LAYERED PRODUCT Kuraray Co., Ltd. (JP) 2023-02-08 EP disclosed
CN-115348979-A Methacrylic copolymer, composition, molded body, method for producing film or sheet, and laminate 株式会社可乐丽 2022-11-15 CN disclosed
EP-3418326-B1 THERMOPLASTIC RESIN FILM, ITS MANUFACTURING METHOD AND LAMINATED BODY KURARAY CO (JP) 2022-04-13 EP disclosed
CN-110352212-B Biaxially stretched acrylic resin film and method for producing same 株式会社可乐丽 2022-04-01 CN disclosed
US-11052645-B2 Thermoplastic resin film, its manufacturing method, and laminated body KURARAY CO., LTD. (JP) 2021-07-06 US disclosed
US-20190055393-A1 THERMOPLASTIC RESIN FILM, ITS MANUFACTURING METHOD, AND LAMINATED BODY KURARAY CO., LTD. (JP) 2019-02-21 US disclosed
EP-3418326-A1 THERMOPLASTIC RESIN FILM AND PRODUCTION METHOD THREREFOR, AND LAMINATE Kuraray Co., Ltd. (JP) 2018-12-26 EP disclosed
EP-3284784-A1 METHACRYLIC RESIN COMPOSITION Kuraray Co., Ltd. (JP) 2018-02-21 EP disclosed
EP-3162818-A1 METHACRYLIC RESIN OR METHACRYLIC RESIN COMPOSITION Kuraray Co., Ltd. (JP) 2017-05-03 EP disclosed
US-8540904-B2 Composition for ultraviolet absorbent substance and ultraviolet absorbent substance comprising same SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2013-09-24 US disclosed
US-20120313058-A1 COMPOSITION FOR ULTRAVIOLET ABSORBENT SUBSTANCE AND ULTRAVIOLET ABSORBENT SUBSTANCE COMPRISING SAME SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2012-12-13 US disclosed
US-4260770-A Naphtholactam dyes CIBA-GEIGY AKTIENGESELLSCHAFT (DE) 1981-04-07 US disclosed
US-4256896-A THIAZOLE, IMIDAZOLINE, AND OXAZOLINE DYES; DISPERSE DYES; ANIONIC DYES; TEXTILES CIBA-GEIGY AKTIENGESELLSCHAFT (DE) 1981-03-17 US disclosed
US-4219651-A FLUORESCENT DYES, OPTICAL BRIGHTENERS; CHEMICAL INTERMEDIATES HOECHST AKTIENGESELLSCHAFT (DE) 1980-08-26 US disclosed