Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.44 |
| ▸ | F10 | P00742 | 3/20 | 0.44 |
| ▸ | F7 | P08709 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.38 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7409101 | 0.87 | F10 (0.60) | F2F10F7KLK1KLK5 | |
| SCHEMBL7409412 | 0.80 | MAPT (0.48) | F2F10F7LMNAMAPT | |
| SCHEMBL11330804 | 0.78 | LMNA (0.59) | LMNAMAPTHTTMEN1ALDH1A1 | |
| SCHEMBL7489169 | 0.77 | F10 (0.53) | F2F10F7MAPTMEN1 | |
| SCHEMBL7401334 | 0.76 | NPSR1 (0.48) | F2F10F7ALDH1A1KDM4E | |
| SCHEMBL7405317 | 0.70 | F10 (0.59) | F2F10F7MAPTALDH1A1 | |
| SCHEMBL7409276 | 0.70 | F10 (0.63) | F2F10F7TPSAB1PRSS1 | |
| SCHEMBL22164295 | 0.70 | PKM (0.48) | LMNAMAPTHTTMEN1ALDH1A1 | |
| SCHEMBL6336736 | 0.70 | MAPT (0.43) | LMNAMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL9028427 | 0.69 | F10 (0.48) | F2F10F7LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026932-A1 | BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |