SCHEMBL1133508

SCHEMBL1133508

Cc1c(C#N)c(=O)oc2cc(O)ccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HSD17B3 P37058 5/20 1.00
ALPL P05186 3/20 0.60
MAOB P27338 6/20 0.58
MAOA P21397 5/20 0.58
ALPI P09923 2/20 0.57
ESR1 P03372 3/20 0.56
ESR2 Q92731 3/20 0.56
ERAP1 Q9NZ08 1/20 0.56
PDE2A O00408 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29206959 0.84 HSD17B3 (0.73) HSD17B3ALPLMAOBMAOAALPI
SCHEMBL31366988 0.82 HSD17B3 (1.00) HSD17B3MAOBESR1ESR2ERAP1
SCHEMBL591899 0.82 HSD17B3 (1.00) HSD17B3MAOBESR1ESR2ERAP1
SCHEMBL29206927 0.82 HSD17B3 (0.69) HSD17B3ALPLMAOBMAOAALPI
SCHEMBL29226081 0.82 HSD17B3 (0.69) HSD17B3ALPLMAOBMAOAALPI
SCHEMBL29226062 0.82 HSD17B3 (0.69) HSD17B3ALPLMAOBMAOAALPI
SCHEMBL28446883 0.80 HSD17B3 (0.96) HSD17B3MAOBESR1ESR2ERAP1
SCHEMBL15842341 0.79 ALPL (0.74) HSD17B3ALPLMAOBMAOAALPI
SCHEMBL11874784 0.79 HSD17B3 (0.65) HSD17B3MAOBMAOA
SCHEMBL3306142 0.78 HSD17B3 (0.64) HSD17B3MAOAESR1ESR2ERAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010154-A Method for preparing high-whiteness cubic nano calcium carbonate at low temperature 湖北三峡实验室 2026-05-12 CN claimed
US-20100038632-A1 ELECTROLUMINESCENT DEVICE OLED-T LIMITED (GB) 2010-02-18 US claimed
US-20040092738-A1 Silent mark for oil product and detection method thereto SK ENERGY CO., LTD. (KR) 2004-05-13 US claimed
EP-1309572-A4 SILENT MARK FOR OIL PRODUCT AND DETECTION METHOD THERETO SK CORP (KR) 2004-03-17 EP claimed
EP-1309572-A1 SILENT MARK FOR OIL PRODUCT AND DETECTION METHOD THERETO SK Corporation (KR) 2003-05-14 EP claimed
JP-2003504327-A 2003-02-04 JP claimed
EP-1223928-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS Prendergast, Patrick Thomas (IE) 2002-07-24 EP claimed
WO-2002004431-A1 SILENT MARK FOR OIL PRODUCT AND DETECTION METHOD THERETO SK CORPORATION (KR) 2002-01-17 WO claimed
WO-2001003681-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS PRENDERGAST PATRICK T (IE) 2001-01-18 WO claimed
CN-122010154-A Method for preparing high-whiteness cubic nano calcium carbonate at low temperature 湖北三峡实验室 2026-05-12 CN disclosed
US-20230313261-A1 Biological Indicator Comprising Genetically-Modified Test Microorganism SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2023-10-05 US disclosed
US-20230193347-A1 Biological Indicator with Test Microorganisms Enveloped by Wax Composition SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2023-06-22 US disclosed
CN-116194158-A Biological indicator comprising genetically modified test microorganism 3M创新有限公司 2023-05-30 CN disclosed
US-20230110772-A1 Immobilized pH Indicator for Biological Indicator Growth Indication SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2023-04-13 US disclosed
EP-0937149-A2 GLUCURONIDE REPRESSORS AND USES THEREOF Cambia Biosystems LLC (US) 1999-08-25 EP disclosed
US-5879906-A GENE AND PROTEIN SEQUENCES OF GLUCURONIDE REPRESSORS AND USE OF THE REPRESSOR FOR CONTROLLING GENE EXPRESSION AND DETECTING GLUCURONIDES, WHILE PROVIDING OTHER RELATED ADVANTAGES. CAMBIA BIOSYSTEMS LLC (US) 1999-03-09 US disclosed
WO-1997049813-A2 GLUCURONIDE REPRESSORS AND USES THEREOF CAMBIA BIOSYSTEMS LLC (US) 1997-12-31 WO disclosed
EP-0171645-B1 2H-1-BENZOPYRAN-2-ON DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS Roche Diagnostics GmbH (DE) 1988-11-30 EP disclosed
US-4670439-A INHIBITING ALLERGIC REACTIONS BOEHRINGER MANNHEIM GMBH (DE) 1987-06-02 US disclosed
EP-0171645-A1 2H-1-benzopyran-2-on derivatives, process for their preparation and medicines containing these compounds Roche Diagnostics GmbH (DE) 1986-02-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040092738-A1 Silent mark for oil product and detection method thereto NOTUM, SQLE, MSMO1 HSD17B3 114/4885ALPL 182/4885MAOB 516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.