Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529026 | 0.84 | KMT2A (0.59) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 | |
| Water SCHEMBL8887299 | 0.84 | AKR1C3 (0.51) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL2346165 | 0.84 | AKR1C3 (0.51) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL5495359 | 0.82 | ATIC (0.54) | KMT2AMEN1 | |
| SCHEMBL11505875 | 0.82 | CA1 (0.49) | ALDH1A1TDP1RAB9AMAPK1L3MBTL1 | |
| SCHEMBL11337097 | 0.81 | L3MBTL1 (0.48) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL11595620 | 0.81 | L3MBTL1 (0.57) | ALDH1A1TDP1RAB9AL3MBTL1NPSR1 | |
| SCHEMBL11131080 | 0.79 | KMT2A (0.56) | KMT2AMEN1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL474709 | 0.77 | KMT2A (0.70) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL5340030 | 0.77 | MEN1 (0.89) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258033-A | CORONARY VASODILATORS EFFECTIVE IN ISCHEMIC HEART DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-03-24 | — | — | US | disclosed |