Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11335359 | 0.81 | KMT2A (0.57) | L3MBTL1ALDH1A1MAPK1RAB9APOLB | |
| Water SCHEMBL8887299 | 0.80 | AKR1C3 (0.51) | L3MBTL1RAB9APOLBKMT2AMEN1 | |
| SCHEMBL2346165 | 0.80 | AKR1C3 (0.51) | L3MBTL1RAB9APOLBKMT2AMEN1 | |
| SCHEMBL12852560 | 0.80 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1MAPK1BRAFRAB9A | |
| SCHEMBL5495359 | 0.78 | ATIC (0.54) | KMT2AMEN1 | |
| SCHEMBL11505875 | 0.78 | CA1 (0.49) | L3MBTL1ALDH1A1MAPK1RAB9APOLB | |
| Hydrochloric Acid SCHEMBL27639556 | 0.78 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1MAPK1BRAFRAB9A | |
| SCHEMBL6686241 | 0.77 | RAB9A (0.70) | L3MBTL1ALDH1A1MAPK1RAB9APOLB | |
| SCHEMBL11595620 | 0.77 | L3MBTL1 (0.57) | L3MBTL1ALDH1A1RAB9ALMNAMAPT | |
| SCHEMBL10389972 | 0.76 | SMN1; SMN2 (0.54) | L3MBTL1ALDH1A1RAB9APOLBNR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258033-A | CORONARY VASODILATORS EFFECTIVE IN ISCHEMIC HEART DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-03-24 | — | — | US | disclosed |