SCHEMBL11335481

SCHEMBL11335481

CCC1(c2ccccc2)C(=O)N(Br)C(=O)N(Br)C1=O

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.58
KMT2A Q03164 3/20 0.49
TSHR P16473 2/20 0.49
MEN1 O00255 2/20 0.49
CYP1A2 P05177 1/20 0.49
POLB P06746 1/20 0.49
APEX1 P27695 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
CYP2C19 P33261 4/20 0.48
MMP2 P08253 2/20 0.42
MMP3 P08254 2/20 0.42
MMP9 P14780 2/20 0.42
ELANE P08246 2/20 0.41
NPSR1 Q6W5P4 1/20 0.40
BACE1 P56817 1/20 0.37
BACE2 Q9Y5Z0 1/20 0.37
MITF O75030 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17794053 0.80 LMNA (0.68) LMNAKMT2ATSHRMEN1CYP1A2
SCHEMBL11864115 0.79 LMNA (0.68) LMNAKMT2ATSHRMEN1CYP1A2
SCHEMBL11857604 0.76 LMNA (0.68) LMNAKMT2ATSHRMEN1CYP1A2
SCHEMBL22680911 0.76 LMNA (0.55) LMNAKMT2ATSHRMEN1CYP1A2
SCHEMBL10629919 0.73 MITF (0.43) LMNAKMT2ATSHRMEN1CYP1A2
SCHEMBL11426802 0.73 LMNA (0.64) LMNAKMT2ATSHRMEN1CYP1A2
Eterobarb SCHEMBL35417 0.73 LMNA (1.00) LMNAKMT2ATSHRMEN1CYP1A2
SCHEMBL11925118 0.71 LMNA (0.56) LMNAKMT2ATSHRMEN1CYP1A2
SCHEMBL11663947 0.70 LMNA (0.49) LMNAKMT2ATSHRMEN1CYP1A2
SCHEMBL5494690 0.70 LMNA (0.73) LMNAKMT2ATSHRMEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4032348-A METHOD FOR FORMING PHASE HOLOGRAMS FUJI PHOTO FILM CO., LTD. (JA) 1977-06-28 US claimed
US-4307187-A THIOSULFONIC ACIDS PREVENT HEAT FOG WHEN STORED, REDUCING AGENTS FUJI PHOTO FILM CO., LTD. (JP) 1981-12-22 US disclosed
US-4237215-A DECOMPOSING N-HALO COMPOUND IN PRESENCE OF ORGANIC SILVER SALT TO PRODUCE SILVER HALIDE FUJI PHOTO FILM CO., LTD. (JP) 1980-12-02 US disclosed
US-4213784-A Process for producing heat developable light-sensitive compositions and elements FUJI PHOTO FILM CO., LTD. (JP) 1980-07-22 US disclosed
US-4193804-A REACTING AN ORGANIC SILVER SALT AND A HALOGEN-RELEASING COMPOUND TO FORM THE SILVER HALIDE WHILE CONTROLLING REDOX POTENTIAL FUJI PHOTO FILM CO., LTD. (JP) 1980-03-18 US disclosed
US-4128428-A ORGANIC SILVER SALT, N-HALO COMPOUND, REDUCING AGENT, IRON COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1978-12-05 US disclosed
US-4032348-A METHOD FOR FORMING PHASE HOLOGRAMS FUJI PHOTO FILM CO., LTD. (JA) 1977-06-28 US disclosed