Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 8/20 | 0.94 |
| ▸ | HTR2A | P28223 | 7/20 | 0.94 |
| ▸ | DRD2 | P14416 | 7/20 | 0.94 |
| ▸ | HTR1A | P08908 | 6/20 | 0.94 |
| ▸ | HTR2C | P28335 | 5/20 | 0.94 |
| ▸ | HTR2B | P41595 | 5/20 | 0.94 |
| ▸ | DRD4 | P21917 | 4/20 | 0.94 |
| ▸ | HTR1D | P28221 | 3/20 | 0.94 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.94 |
| ▸ | DRD1 | P21728 | 3/20 | 0.94 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.94 |
| ▸ | LMNA | P02545 | 2/20 | 0.94 |
| ▸ | MEN1 | O00255 | 2/20 | 0.94 |
| ▸ | TP53 | P04637 | 2/20 | 0.94 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.94 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.94 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.94 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.94 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.94 |
| ▸ | TSHR | P16473 | 2/20 | 0.94 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mianserin SCHEMBL23326358 | 0.97 | DRD3 (1.00) | DRD3HTR2ADRD2HTR1AHTR2C | |
| Mianserin SCHEMBL18020 | 0.97 | DRD3 (1.00) | DRD3HTR2ADRD2HTR1AHTR2C | |
| Mianserin SCHEMBL29356897 | 0.97 | DRD3 (1.00) | DRD3HTR2ADRD2HTR1AHTR2C | |
| Mianserin SCHEMBL9122085 | 0.97 | DRD3 (1.00) | DRD3HTR2ADRD2HTR1AHTR2C | |
| Mianserin SCHEMBL353397 | 0.97 | DRD3 (1.00) | DRD3HTR2ADRD2HTR1AHTR2C | |
| Mianserin SCHEMBL9752060 | 0.96 | DRD3 (0.97) | DRD3HTR2ADRD2HTR1AHTR2C | |
| Mianserin SCHEMBL8344416 | 0.96 | DRD3 (0.97) | DRD3HTR2ADRD2HTR1AHTR2C | |
| Mianserin SCHEMBL340474 | 0.96 | MEN1 (1.00) | DRD3HTR2ADRD2HTR1AHTR2C | |
| Mianserin SCHEMBL29366576 | 0.96 | MEN1 (1.00) | DRD3HTR2ADRD2HTR1AHTR2C | |
| Mianserin SCHEMBL11336834 | 0.96 | HTR2A (0.97) | DRD3HTR2ADRD2HTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2193186-B1 | HYDRAULIC OIL FOR USE IN CONSTRUCTION MACHINERY | SHELL INT RESEARCH (NL) | 2011-11-09 | — | — | EP | disclosed |
| US-20100298186-A1 | HYDRAULIC OIL FOR USE IN CONSTRUCTION MACHINERY | SHELL OIL COMPANY | 2010-11-25 | — | — | US | disclosed |
| EP-2193186-A1 | HYDRAULIC OIL FOR USE IN CONSTRUCTION MACHINERY | SHELL INTERNATIONAL RESEARCH MAATSCHAPPIJ B.V. (NL) | 2010-06-09 | — | — | EP | disclosed |
| WO-2009040658-A1 | HYDRAULIC OIL FOR USE IN CONSTRUCTION MACHINERY | SHOWA SHELL SEKIYU K.K. (NL) | 2009-04-02 | — | — | WO | disclosed |
| US-4985155-A | Graft Polymer of an Acrylate on a Polysiloxane | NISSIN CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |