SCHEMBL11336972

SCHEMBL11336972

COC(=O)C1CCC=C(C(=O)O)C1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 1/20 0.38
BRD4 O60885 1/20 0.38
ALDH1A1 P00352 2/20 0.37
TSHR P16473 2/20 0.36
LMNA P02545 1/20 0.36
KDM4E B2RXH2 1/20 0.35
KMT2A Q03164 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
HSD17B10 Q99714 1/20 0.35
SLC6A1 P30531 1/20 0.34
SLC6A13 Q9NSD5 1/20 0.34
CHRM3 P20309 1/20 0.34
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL418069 0.86 CHRM3 (0.45) BRD4ALDH1A1LMNAKDM4EKMT2A
SCHEMBL1826547 0.84 GABRR1 (0.39) GABRR1TSHRLMNAHSD17B10SLC6A1
SCHEMBL11339966 0.82 PDK1 (0.42) ALDH1A1KDM4EKMT2ANPC1RAB9A
SCHEMBL11333527 0.82 GABRR1 (0.35) GABRR1TSHRLMNASLC6A1SLC6A13
SCHEMBL701801 0.80 GABRR1 (0.44) GABRR1TSHRLMNAKMT2AHSD17B10
SCHEMBL10684598 0.77 SMN1; SMN2 (0.39) BRD4ALDH1A1LMNAKDM4EKMT2A
SCHEMBL13159214 0.75 GABRR1 (0.40) GABRR1TSHRLMNAKMT2AHSD17B10
SCHEMBL22731626 0.75 GABRR1 (0.40) GABRR1TSHRLMNAKMT2AHSD17B10
SCHEMBL14821051 0.73 BRD4 (0.36) BRD4ALDH1A1KDM4EKMT2ASMN1; SMN2
SCHEMBL11331535 0.72 TSHR (0.63) GABRR1BRD4ALDH1A1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4255588-A Synthesis of cyclohexene dicarboxylic acid esters GULF OIL CORPORATION (US) 1981-03-10 US disclosed