Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.35 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | OAT | P04181 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1826545 | 0.86 | — | — | |
| SCHEMBL11336972 | 0.84 | GABRR1 (0.38) | GABRR1TSHRSLC6A1SLC6A13LMNA | |
| SCHEMBL701801 | 0.81 | GABRR1 (0.44) | GABRR1TSHRSLC6A1SLC6A13BLM | |
| SCHEMBL11333527 | 0.80 | GABRR1 (0.35) | GABRR1TSHRSLC6A1SLC6A13BLM | |
| SCHEMBL11339966 | 0.80 | PDK1 (0.42) | HSD17B10 | |
| SCHEMBL14259674 | 0.71 | GABRR1 (0.45) | GABRR1TSHRSLC6A1SLC6A13BLM | |
| SCHEMBL12491592 | 0.70 | GABRR1 (0.41) | GABRR1TSHRSLC6A1SLC6A13BLM | |
| SCHEMBL418069 | 0.70 | CHRM3 (0.45) | BLMLMNAHSD17B10 | |
| SCHEMBL2867698 | 0.69 | GABRR1 (0.44) | GABRR1TSHRSLC6A1SLC6A13BLM | |
| SCHEMBL12491780 | 0.69 | GABRR1 (0.40) | GABRR1TSHRSLC6A1SLC6A13BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318352-A2 | CYCLOHEXENYL MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Bristol-Myers Squibb Company (US) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010009068-A2 | CYCLOHEXENYL MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-01-21 | — | — | WO | disclosed |