Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11336972 | 0.86 | GABRR1 (0.38) | CHRM3LMNABRD4HSD17B10KMT2A | |
| SCHEMBL2531784 | 0.79 | CHRM3 (0.47) | CHRM3LMNACHRM2CHRM4CHRM5 | |
| SCHEMBL22571128 | 0.79 | CHRM3 (0.47) | CHRM3LMNACHRM2CHRM4CHRM5 | |
| SCHEMBL1826545 | 0.77 | — | — | |
| SCHEMBL10684598 | 0.77 | SMN1; SMN2 (0.39) | LMNABRD4KMT2ATP53ALDH1A1 | |
| SCHEMBL11337461 | 0.76 | CA12 (0.34) | LMNAHSD17B10ALDH1A1KDM4E | |
| SCHEMBL11333460 | 0.76 | PDK1 (0.42) | LMNAKMT2AALDH1A1KDM4E | |
| SCHEMBL14821051 | 0.73 | BRD4 (0.36) | BRD4KMT2ATP53ALDH1A1KDM4E | |
| SCHEMBL11340754 | 0.73 | ALDH1A1 (0.39) | CHRM3LMNACHRM2CHRM4CHRM5 | |
| SCHEMBL818273 | 0.72 | LMNA (0.46) | CHRM3LMNACHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10322998-B2 | Heterogeneous foldamers containing α, β, and/or γ-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-06-18 | — | — | US | disclosed |
| US-20120021530-A1 | HETEROGENEOUS FOLDAMERS CONTAINING alpha, beta, and/or gamma-AMINO ACIDS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2012-01-26 | — | — | US | disclosed |
| US-7858737-B2 | Heterogeneous foldamers containing α, β, and/or γ-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-12-28 | — | — | US | disclosed |
| US-6958384-B2 | Polypeptides containing γ-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2005-10-25 | — | — | US | disclosed |
| US-20040116654-A1 | Heterogeneous foldamers containing alpha, beta, and/or gamma-amino acids | NATIONAL SCIENCE FOUNDATION | 2004-06-17 | — | — | US | disclosed |
| US-20030211999-A1 | Polypeptides containing gamma-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2003-11-13 | — | — | US | disclosed |
| US-4255588-A | Synthesis of cyclohexene dicarboxylic acid esters | GULF OIL CORPORATION (US) | 1981-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10322998-B2 | Heterogeneous foldamers containing α, β, and/or γ-amino acids | DNPEP, PRKCSH, BCAT1 | CHRM3 4481/4885LMNA 1950/4885CHRM2 4690/4885 |
| US-20120021530-A1 | HETEROGENEOUS FOLDAMERS CONTAINING alpha, beta, and/or gamma-AMINO ACIDS | DNPEP, PRKCSH, YWHAZ | CHRM3 4369/4885LMNA 1962/4885CHRM2 4634/4885 |
| US-20030211999-A1 | Polypeptides containing gamma-amino acids | PEPD, DNPEP, ANPEP | CHRM3 4782/4885LMNA 660/4885CHRM2 4788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.