Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24575947 | 0.85 | HPGDS (0.57) | HPGDSLMNATSHRALDH1A1KMT2A | |
| SCHEMBL1694742 | 0.85 | LMNA (0.60) | HPGDSLMNATSHRCYP2D6ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5883141 | 0.83 | LMNA (0.58) | HPGDSLMNATSHRCYP2D6ALDH1A1 | |
| SCHEMBL1386996 | 0.81 | LMNA (0.79) | HPGDSLMNATSHRALDH1A1KMT2A | |
| SCHEMBL425360 | 0.81 | HPGDS (0.53) | HPGDSLMNATSHRCYP2D6ALDH1A1 | |
| SCHEMBL1799045 | 0.81 | HPGDS (0.53) | HPGDSLMNATSHRCYP2D6ALDH1A1 | |
| SCHEMBL425361 | 0.81 | ALDH1A1 (0.58) | HPGDSLMNATSHRALDH1A1KMT2A | |
| SCHEMBL1386995 | 0.81 | HPGDS (0.58) | HPGDSLMNATSHRCYP2D6ALDH1A1 | |
| SCHEMBL13324507 | 0.81 | HPGDS (0.53) | HPGDSLMNATSHRCYP2D6ALDH1A1 | |
| SCHEMBL29902958 | 0.81 | LMNA (0.51) | HPGDSLMNATSHRALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4292427-A | BACTERICIDES | MERCK & CO., INC. (US) | 1981-09-29 | — | — | US | disclosed |
| US-4210750-A | BY TREATMENT OF 3-HYDROXYMETHYL DERIVATIVE WITH TRIFLUOROACETYL ISOCYANATE | MERCK & CO., INC. (US) | 1980-07-01 | — | — | US | disclosed |