SCHEMBL11337033

SCHEMBL11337033

C=C(C)S(=O)(=O)Nc1ccc(Nc2ccc(C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
GAA P10253 2/20 0.50
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
HPGD P15428 3/20 0.46
MAPT P10636 1/20 0.45
SNCA P37840 1/20 0.45
G6PD P11413 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
PKM P14618 1/20 0.41
TGM2 P21980 1/20 0.41
ALDH1A1 P00352 2/20 0.40
LMNA P02545 1/20 0.40
ALOX12 P18054 1/20 0.40
FKBP1A P62942 1/20 0.40
CA12 O43570 1/20 0.40
CA9 Q16790 1/20 0.40
HDAC4 P56524 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11340331 0.86 GAA (0.53) MEN1KMT2AGAACA1CA2
SCHEMBL11348254 0.76 TGM2 (0.59) MEN1KMT2AGAACA1CA2
SCHEMBL7258179 0.74 CA1 (0.61) MEN1KMT2AGAACA1CA2
SCHEMBL7438763 0.74 CA1 (0.61) MEN1KMT2AGAACA1CA2
SCHEMBL11705580 0.72 MEN1 (0.86) MEN1KMT2AGAACA1CA2
SCHEMBL50079 0.71 HPGD (0.78) MEN1KMT2AGAAHPGDMAPT
SCHEMBL9516537 0.71 HPGD (0.78) MEN1KMT2AGAAHPGDMAPT
SCHEMBL108881 0.71 HPGD (0.78) MEN1KMT2AGAAHPGDMAPT
SCHEMBL11050137 0.70 HPGD (0.56) MEN1KMT2AGAACA1CA2
SCHEMBL11773321 0.69 SNCA (0.74) MEN1KMT2AGAACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4298522-A HEAT AND AGING RESISTANCE NIPPON ZEON CO. LTD. (JP) 1981-11-03 US disclosed