SCHEMBL11348254

SCHEMBL11348254

C=CS(=O)(=O)Nc1ccc(Nc2ccc(C)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 2/20 0.59
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
GAA P10253 1/20 0.51
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
HPGD P15428 2/20 0.47
SNCA P37840 1/20 0.46
SRC P12931 1/20 0.45
TEAD4 Q15561 1/20 0.44
GSTO1 P78417 1/20 0.44
MAPK1 P28482 2/20 0.42
BRD4 O60885 1/20 0.41
FKBP1A P62942 1/20 0.41
CA12 O43570 1/20 0.41
CA9 Q16790 1/20 0.41
ALDH1A1 P00352 3/20 0.40
MAPT P10636 2/20 0.40
LMNA P02545 1/20 0.40
GFER P55789 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11143174 0.94 TGM2 (0.66) TGM2MEN1KMT2AGAACA1
SCHEMBL11335118 0.83 TGM2 (0.61) TGM2MEN1KMT2AGAACA1
SCHEMBL7438763 0.80 CA1 (0.61) MEN1KMT2AGAACA1CA2
SCHEMBL11337033 0.76 MEN1 (0.50) TGM2MEN1KMT2AGAACA1
SCHEMBL94878 0.76 TGM2 (0.68) TGM2KMT2ACA1CA2SRC
SCHEMBL5102141 0.76 TGM2 (0.61) TGM2CA1CA2SRCTEAD4
SCHEMBL28047424 0.74 TGM2 (0.59) TGM2MEN1KMT2AHPGDTEAD4
SCHEMBL9179590 0.74 TGM2 (0.59) TGM2GAACA1CA2HPGD
SCHEMBL1424434 0.74 TGM2 (0.64) TGM2MEN1KMT2ACA1CA2
SCHEMBL11345686 0.74 MEN1 (0.68) MEN1KMT2AGAACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4298522-A HEAT AND AGING RESISTANCE NIPPON ZEON CO. LTD. (JP) 1981-11-03 US disclosed