SCHEMBL11340331

SCHEMBL11340331

C=C(C)S(=O)(=O)Nc1ccc(Nc2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.53
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
GFER P55789 2/20 0.53
MAPT P10636 6/20 0.50
POLB P06746 1/20 0.50
KEAP1 Q14145 1/20 0.47
ALDH1A1 P00352 4/20 0.46
HSD17B10 Q99714 2/20 0.46
PTGS2 P35354 2/20 0.46
ALOX15 P16050 1/20 0.46
TSHR P16473 1/20 0.46
ALOX12 P18054 1/20 0.46
PTGS1 P23219 1/20 0.46
SLC6A2 P23975 1/20 0.46
MAPK1 P28482 1/20 0.46
HTR2B P41595 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
HSP90AA1 P07900 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11337033 0.86 MEN1 (0.50) GAAMEN1KMT2AMAPTPOLB
SCHEMBL28799223 0.79 ALDH1A1 (0.56) GAAMEN1KMT2AGFERMAPT
Diphenylamine SCHEMBL7220745 0.76 HSD17B10 (0.67) GAAMEN1KMT2AMAPTPOLB
Diphenylamine SCHEMBL5712060 0.76 HSD17B10 (0.67) GAAMEN1KMT2AMAPTPOLB
SCHEMBL9231787 0.75 KEAP1 (0.56) GAAMEN1KMT2AGFERKEAP1
SCHEMBL29092698 0.75 KEAP1 (0.56) GAAMEN1KMT2AGFERMAPT
SCHEMBL9479898 0.75 KEAP1 (0.83) GAAMEN1KMT2AKEAP1ALDH1A1
SCHEMBL11335118 0.74 TGM2 (0.61) GAAMEN1KMT2AGFERMAPT
Diphenylamine SCHEMBL1626446 0.72 MAPT (0.61) GAAMEN1KMT2AGFERMAPT
Diphenylamine SCHEMBL29875738 0.72 MAPT (0.61) GAAMEN1KMT2AGFERMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4298522-A HEAT AND AGING RESISTANCE NIPPON ZEON CO. LTD. (JP) 1981-11-03 US claimed
US-4298522-A HEAT AND AGING RESISTANCE NIPPON ZEON CO. LTD. (JP) 1981-11-03 US disclosed