Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11333977 | 0.84 | KDM4E (0.62) | KDM4EPKMCYP2C19LMNASMN1; SMN2 | |
| SCHEMBL11340545 | 0.84 | KDM4E (0.61) | KDM4EPKMCYP2C19LMNASMN1; SMN2 | |
| SCHEMBL5083344 | 0.80 | KDM4E (1.00) | KDM4EPKMCYP2C19LMNASMN1; SMN2 | |
| SCHEMBL11338190 | 0.74 | KDM4E (0.72) | KDM4EPKMCYP2C19LMNASMN1; SMN2 | |
| SCHEMBL12608899 | 0.72 | CYP2C19 (0.85) | KDM4EPKMCYP2C19LMNASMN1; SMN2 | |
| SCHEMBL17716275 | 0.68 | ELANE (0.48) | KDM4ECYP2C19MEN1KMT2AELANE | |
| SCHEMBL4731087 | 0.67 | KDM4E (0.77) | KDM4EPKMCYP2C19LMNASMN1; SMN2 | |
| Kebuzone SCHEMBL231224 | 0.67 | LMNA (0.58) | KDM4ECYP2C19LMNASMN1; SMN2MEN1 | |
| Kebuzone SCHEMBL6375816 | 0.66 | LMNA (0.56) | KDM4ECYP2C19LMNASMN1; SMN2MEN1 | |
| SCHEMBL1903678 | 0.65 | KDM4E (0.62) | KDM4EPKMCYP2C19LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273873-A | BONDING SYNTHETIC FIBRINOLYTIC COMPOUND OR ENZYME | UNITIKA LTD. (JP) | 1981-06-16 | — | — | US | disclosed |