Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | CETP | P11597 | 15/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11338188 | 0.89 | MAPT (0.51) | MAPTCETPTP53THRBSMN1; SMN2 | |
| SCHEMBL11336023 | 0.77 | NPC1 (0.53) | MAPTTP53SMN1; SMN2NPC1RAB9A | |
| SCHEMBL15745638 | 0.75 | NPC1 (0.66) | MAPTCETPTP53THRBSMN1; SMN2 | |
| SCHEMBL11167498 | 0.75 | NPC1 (0.56) | MAPTCETPTP53THRBSMN1; SMN2 | |
| SCHEMBL11446660 | 0.74 | NPC1 (0.64) | MAPTCETPTP53THRBSMN1; SMN2 | |
| SCHEMBL9181309 | 0.72 | ENPP2 (0.33) | SMN1; SMN2 | |
| SCHEMBL14266186 | 0.71 | MAPT (0.67) | MAPTCETPTP53THRBSMN1; SMN2 | |
| SCHEMBL10964364 | 0.71 | ENPP2 (0.35) | SMN1; SMN2 | |
| SCHEMBL9681997 | 0.70 | NPC1 (0.71) | MAPTCETPTP53THRBSMN1; SMN2 | |
| SCHEMBL11160763 | 0.70 | NPC1 (0.56) | MAPTCETPTP53THRBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0033459-A1 | Benzoxazolylstilbenes, processes for their production and their use as optical brighteners | BAYER AG (DE) | 1981-08-12 | — | — | EP | disclosed |