Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11571467 | 0.88 | PTGDR2 (0.38) | CHRM3CHRM2PTGDR2OPRM1SIGMAR1 | |
| SCHEMBL11571464 | 0.74 | CHRM2 (0.40) | CHRM3CHRM2ATMSLC18A3L3MBTL1 | |
| SCHEMBL26879524 | 0.70 | SLC18A3 (0.50) | ATMSLC18A3L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL11456753 | 0.68 | LMNA (0.45) | CHRM3CHRM2PTGDR2ATML3MBTL1 | |
| SCHEMBL11344671 | 0.66 | ALDH1A1 (0.36) | CHRM3CHRM2L3MBTL1OPRM1SIGMAR1 | |
| SCHEMBL11438366 | 0.65 | KMT2A (0.40) | CHRM3CHRM2PTGDR2OPRM1SIGMAR1 | |
| SCHEMBL3375958 | 0.65 | GRIN2B (0.60) | SLC18A3L3MBTL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL11331790 | 0.65 | ALDH1A1 (0.47) | CHRM3CHRM2PTGDR2ATMSLC18A3 | |
| SCHEMBL20063747 | 0.65 | SLC18A3 (0.68) | SLC18A3L3MBTL1ALDH1A1KDM4EKMT2A | |
| SCHEMBL16544565 | 0.63 | SLC18A3 (0.45) | SLC18A3OPRM1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE30837-E | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1981-12-29 | — | — | US | disclosed |
| US-4169156-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-09-25 | — | — | US | disclosed |