Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAC1 | P63000 | 2/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269321 | 0.82 | MAPT (0.61) | MEN1TSHRKMT2AATMMAPT | |
| SCHEMBL11336031 | 0.81 | PTGDR (0.49) | MEN1TSHRKMT2AATMMAPT | |
| SCHEMBL11281002 | 0.80 | NPC1 (0.47) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL11339510 | 0.79 | ALDH1A1 (0.59) | MEN1TSHRKMT2AATMMAPT | |
| SCHEMBL11329822 | 0.77 | NOTUM (0.46) | MEN1TSHRKMT2AATMMAPT | |
| SCHEMBL13950389 | 0.76 | MEN1 (0.56) | RAC1CYP11B2MEN1TSHRKMT2A | |
| SCHEMBL11329014 | 0.76 | ADORA2A (0.57) | MEN1TSHRKMT2AATMMAPT | |
| SCHEMBL11335510 | 0.76 | L3MBTL1 (0.49) | CYP11B2MEN1TSHRKMT2AATM | |
| SCHEMBL3399073 | 0.76 | CYP1A2 (0.64) | CYP11B2MAPTCYP1A2ALDH1A1HPGD | |
| SCHEMBL11631313 | 0.75 | MEN1 (0.39) | MEN1TSHRKMT2AATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251527-A | ANTIINFLAMMATORY AGENTS | DIAMOND SHAMROCK CORPORATION (US) | 1981-02-17 | — | — | US | disclosed |