Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281002 | 0.84 | NPC1 (0.47) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11335510 | 0.83 | L3MBTL1 (0.49) | ADORA2AADORA1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11269321 | 0.82 | MAPT (0.61) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11631313 | 0.79 | MEN1 (0.39) | MAPTALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL11339510 | 0.77 | ALDH1A1 (0.59) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11339337 | 0.76 | RAC1 (0.49) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11325516 | 0.73 | ALDH1A1 (0.52) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3398538 | 0.73 | ADORA2A (1.00) | ADORA2AADORA1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11337642 | 0.72 | ALDH1A1 (0.71) | ADORA2AADORA1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11336031 | 0.72 | PTGDR (0.49) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251527-A | ANTIINFLAMMATORY AGENTS | DIAMOND SHAMROCK CORPORATION (US) | 1981-02-17 | — | — | US | disclosed |