Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11345308 | 0.87 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL11339280 | 0.84 | KDM4E (0.54) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL11340384 | 0.83 | ALDH1A1 (0.57) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL11345226 | 0.81 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL11332732 | 0.78 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL11335662 | 0.77 | L3MBTL1 (0.44) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL11494325 | 0.73 | HTT (0.38) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3259352 | 0.73 | KDM4E (0.56) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL11339426 | 0.71 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL11362989 | 0.70 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005205-B1 | SUBSTITUTED 5.6-DIMETHYLPYRROLO(2,3-D)PYRIMIDINES, METHODS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | Troponwerke GmbH & Co. KG (DE) | 1981-09-09 | — | — | EP | disclosed |
| US-4229453-A | ANTIINFLAMMATORY AGENTS, SEDATIVES, ANTICONVULSANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1980-10-21 | — | — | US | disclosed |