Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 10/20 | 0.35 |
| ▸ | CNR1 | P21554 | 8/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19564565 | 0.79 | ALOX15 (0.41) | ALOX15MEN1KMT2AALDH1A1HTR7 | |
| SCHEMBL11043485 | 0.77 | ALOX15 (0.47) | ALOX15MEN1KMT2AALDH1A1HTR7 | |
| SCHEMBL19564571 | 0.77 | MEN1 (0.43) | ALOX15MEN1KMT2AALDH1A1HTR7 | |
| SCHEMBL11016899 | 0.72 | ALOX15 (0.46) | ALOX15MEN1KMT2AALDH1A1HTR7 | |
| SCHEMBL17374357 | 0.70 | ALOX15 (0.41) | ALOX15MEN1KMT2AALDH1A1HTR7 | |
| SCHEMBL17374562 | 0.70 | ALOX15 (0.41) | ALOX15MEN1KMT2AALDH1A1HTR7 | |
| SCHEMBL21933124 | 0.70 | ALOX15 (0.43) | ALOX15MEN1KMT2AALDH1A1HTR7 | |
| SCHEMBL11014819 | 0.69 | HTR7 (0.46) | ALOX15MEN1KMT2AALDH1A1HTR7 | |
| SCHEMBL11090159 | 0.69 | HTR7 (0.46) | ALOX15MEN1KMT2AALDH1A1HTR7 | |
| SCHEMBL11340395 | 0.69 | MEN1 (0.37) | ALOX15MEN1KMT2AALDH1A1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034456-A1 | 3-(Substituted 3- or 5-isoxazolyl)-1-4-, or 5-substituted-2-imidazolidinones, methods for their preparation, compositions containing them and their use as herbicides | PPG INDUSTRIES, INC. (US) | 1981-08-26 | — | — | EP | disclosed |