Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | ADCY5 | O95622 | 2/20 | 0.45 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.44 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11345878 | 0.93 | ADRA1D (0.54) | ADORA2AADRA1DADRA1AADRA1BCARM1 | |
| SCHEMBL11339731 | 0.90 | ADCY5 (0.48) | ADORA2AADRA1DADRA1AADRA1BCARM1 | |
| SCHEMBL11342542 | 0.90 | ADCY5 (0.50) | ADORA2AADRA1DADRA1AADRA1BEGFR | |
| SCHEMBL11475372 | 0.88 | ADCY5 (0.48) | ADORA2AADRA1DADRA1AADRA1BDRD4 | |
| SCHEMBL11485738 | 0.88 | ADCY5 (0.48) | ADORA2AADRA1DADRA1AADRA1BADCY5 | |
| SCHEMBL11476823 | 0.88 | ADCY5 (0.48) | ADORA2AADRA1DADRA1AADRA1BADCY5 | |
| SCHEMBL11340014 | 0.86 | MEN1 (0.48) | ADORA2AADRA1DADRA1AADRA1BADCY5 | |
| SCHEMBL11352914 | 0.85 | NSD3 (0.52) | ADORA2ADRD4ADCY5 | |
| Hydrochloric Acid SCHEMBL11476615 | 0.85 | MEN1 (0.48) | ADORA2AADRA1DADRA1AADRA1BADCY5 | |
| SCHEMBL11477028 | 0.85 | NSD2 (0.51) | ADORA2AADRA1DADRA1AADRA1BADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003558-B1 | 9-(3-PIPERIDINOPROPYL)-PURINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1981-10-21 | — | — | EP | disclosed |
| US-4212866-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANTIEDEMIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1980-07-15 | — | — | US | disclosed |
| EP-0003558-A1 | 9-(3-Piperidinopropyl)-purine derivatives, processes for their preparation, their use and pharmaceutical compositions containing them | Roche Diagnostics GmbH (DE) | 1979-08-22 | — | — | EP | disclosed |