Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.47 |
| ▸ | ADCY5 | O95622 | 4/20 | 0.46 |
| ▸ | CHKA | P35790 | 1/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11342542 | 0.91 | ADCY5 (0.50) | ADCY5FGFR1ADORA2A | |
| SCHEMBL11476823 | 0.90 | ADCY5 (0.48) | PAK1ADCY5FGFR1ADORA2ALMNA | |
| SCHEMBL11347140 | 0.90 | POLB (0.54) | NSD3POLBKMT2AADCY5CHKA | |
| SCHEMBL11339731 | 0.89 | ADCY5 (0.48) | ADCY5FGFR1ADORA2A | |
| SCHEMBL11340014 | 0.89 | MEN1 (0.48) | KMT2AADCY5SLC6A5FGFR1ADORA2A | |
| SCHEMBL11475372 | 0.89 | ADCY5 (0.48) | NSD3ADCY5FGFR1DRD4ADORA2A | |
| SCHEMBL11485738 | 0.89 | ADCY5 (0.48) | NSD3PAK1ADCY5CCR3FGFR1 | |
| SCHEMBL11345878 | 0.88 | ADRA1D (0.54) | POLBADCY5ADORA2A | |
| SCHEMBL11348163 | 0.88 | ADCY5 (0.45) | ADCY5SLC6A5FGFR1ADORA2A | |
| Hydrochloric Acid SCHEMBL11476615 | 0.88 | MEN1 (0.48) | KMT2AADCY5SLC6A5FGFR1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003558-B1 | 9-(3-PIPERIDINOPROPYL)-PURINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1981-10-21 | — | — | EP | disclosed |
| US-4212866-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANTIEDEMIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1980-07-15 | — | — | US | disclosed |
| EP-0003558-A1 | 9-(3-Piperidinopropyl)-purine derivatives, processes for their preparation, their use and pharmaceutical compositions containing them | Roche Diagnostics GmbH (DE) | 1979-08-22 | — | — | EP | disclosed |