Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 2/20 | 0.53 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.51 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.51 |
| ▸ | ADCY5 | O95622 | 4/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11339731 | 0.94 | ADCY5 (0.48) | ADRA1DADRA1AADRA1BEGFRCARM1 | |
| SCHEMBL11342542 | 0.93 | ADCY5 (0.50) | ADRA1DADRA1AADRA1BEGFRADCY5 | |
| SCHEMBL11340483 | 0.93 | ADORA2A (0.48) | ADRA1DADRA1AADRA1BEGFRCARM1 | |
| SCHEMBL11476823 | 0.91 | ADCY5 (0.48) | ADRA1DADRA1AADRA1BADCY5ADORA2A | |
| SCHEMBL11475372 | 0.91 | ADCY5 (0.48) | ADRA1DADRA1AADRA1BEGFRADCY5 | |
| SCHEMBL11485738 | 0.91 | ADCY5 (0.48) | ADRA1DADRA1AADRA1BADCY5ADORA2A | |
| SCHEMBL11352141 | 0.89 | HTR1A (0.50) | ADRA1DADRA1AADRA1BEGFRADCY5 | |
| SCHEMBL11349449 | 0.89 | PIK3CD (0.46) | EGFRADCY5POLB | |
| SCHEMBL11340014 | 0.89 | MEN1 (0.48) | ADRA1DADRA1AADRA1BADCY5ADORA2A | |
| SCHEMBL11342473 | 0.89 | ADRA1D (0.54) | ADRA1DADRA1AADRA1BCARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003558-B1 | 9-(3-PIPERIDINOPROPYL)-PURINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1981-10-21 | — | — | EP | disclosed |
| US-4212866-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANTIEDEMIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1980-07-15 | — | — | US | disclosed |
| EP-0003558-A1 | 9-(3-Piperidinopropyl)-purine derivatives, processes for their preparation, their use and pharmaceutical compositions containing them | Roche Diagnostics GmbH (DE) | 1979-08-22 | — | — | EP | disclosed |