Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | FABP7 | O15540 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11340663 | 0.98 | NPSR1 (0.42) | NPSR1MEN1KMT2ALMNAACHE | |
| SCHEMBL779674 | 0.81 | L3MBTL1 (0.44) | NPSR1MEN1KMT2ALMNAACHE | |
| SCHEMBL779638 | 0.81 | MEN1 (0.43) | NPSR1MEN1KMT2ALMNAACHE | |
| SCHEMBL779700 | 0.79 | ACHE (0.46) | NPSR1MEN1KMT2ALMNAACHE | |
| SCHEMBL5420537 | 0.79 | NPSR1 (0.44) | NPSR1MEN1KMT2ALMNAACHE | |
| SCHEMBL779210 | 0.77 | NPSR1 (0.40) | NPSR1MEN1KMT2ALMNAACHE | |
| SCHEMBL29196552 | 0.75 | NPSR1 (0.38) | NPSR1MEN1KMT2ALMNAACHE | |
| SCHEMBL779274 | 0.75 | ALOX15 (0.41) | NPSR1MEN1KMT2ALMNAACHE | |
| SCHEMBL778323 | 0.75 | MEN1 (0.39) | NPSR1MEN1KMT2ALMNAACHE | |
| SCHEMBL20965616 | 0.72 | ALOX15 (0.39) | NPSR1MEN1KMT2ALMNAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4301280-A | Preparation of 3-substituted cephalosporins | LILLY INDUSTRIES LIMITED (GB) | 1981-11-17 | — | — | US | disclosed |
| EP-0019401-A1 | Process for preparing enamine derivatives, compounds so produced and process for preparing a 3-hydroxy-cephalosporin | Lilly Industries Limited (GB) | 1980-11-26 | — | — | EP | disclosed |