Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11338924 | 0.99 | MEN1 (0.45) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8277196 | 0.76 | PARP1 (0.36) | — | |
| SCHEMBL11777869 | 0.74 | SLC6A4 (0.40) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL2490434 | 0.73 | LMNA (0.46) | SLC6A4 | |
| SCHEMBL3163647 | 0.73 | ADRA2A (0.41) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| Hydrochloric Acid SCHEMBL2490432 | 0.72 | LMNA (0.49) | SLC6A4 | |
| SCHEMBL11340987 | 0.70 | MAOA (0.43) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL11830821 | 0.66 | ADRA2A (0.57) | — | |
| SCHEMBL11335566 | 0.65 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL1981717 | 0.64 | TP53 (0.48) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260626-A | Tetrahydro and imidazoline antisecretory compounds | RICHARDSON-MERRELL INC. (US) | 1981-04-07 | — | — | US | claimed |
| US-4260626-A | Tetrahydro and imidazoline antisecretory compounds | RICHARDSON-MERRELL INC. (US) | 1981-04-07 | — | — | US | disclosed |