Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3858761 | 0.89 | TDP1 (0.38) | PSIP1TDP1ALDH1A1TSHR | |
| SCHEMBL11310449 | 0.86 | TDP1 (0.36) | TDP1ALDH1A1TSHR | |
| SCHEMBL11342294 | 0.79 | — | — | |
| SCHEMBL11347077 | 0.74 | CA9 (0.35) | GAAALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL3299477 | 0.70 | PTGS2 (0.36) | PSIP1TDP1ALDH1A1TSHRMAPT | |
| SCHEMBL3857787 | 0.70 | PTGS2 (0.36) | PSIP1TDP1ALDH1A1TSHRMAPT | |
| SCHEMBL9003676 | 0.69 | RECQL (0.46) | TDP1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL108184 | 0.69 | HTR6 (0.36) | PSIP1PKMTDP1ALDH1A1TSHR | |
| SCHEMBL3132316 | 0.68 | LTA4H (0.53) | GAAALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL11347507 | 0.68 | BCHE (0.43) | PSIP1GAAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251521-A | HYPOGLYCEMIC AGENTS | SANDOZ, INC. (US) | 1981-02-17 | — | — | US | disclosed |