Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GRM6 | O15303 | 2/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30086083 | 0.82 | GRM2 (0.43) | MAPK1MEN1KMT2AALDH1A1GRM6 | |
| SCHEMBL190124 | 0.82 | GRM2 (0.43) | MAPK1MEN1KMT2AALDH1A1GRM6 | |
| SCHEMBL28265693 | 0.82 | NFKB1 (0.35) | MAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL12994214 | 0.77 | MAPK1 (0.35) | MAPK1DGAT1MEN1KMT2AEPHX2 | |
| SCHEMBL8466617 | 0.77 | DGAT1 (0.38) | MAPK1DGAT1MEN1KMT2AEPHX2 | |
| SCHEMBL11028466 | 0.76 | GAA (0.38) | ALDH1A1EPHX2 | |
| SCHEMBL13757818 | 0.73 | — | — | |
| SCHEMBL3372994 | 0.73 | — | — | |
| SCHEMBL295935 | 0.71 | MAPK1 (0.41) | MAPK1DGAT1MEN1KMT2AEPHX2 | |
| Hydrochloric Acid SCHEMBL32674344 | 0.71 | GRM6 (0.33) | ALDH1A1GRM6GRM2GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273704-A | N-Adamantane-substituted tetrapeptide amides | G. D. SEARLE & CO. (US) | 1981-06-16 | — | — | US | disclosed |