Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11340978 | 0.82 | MAPK1 (0.37) | MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL9252549 | 0.79 | NFKB1 (0.36) | NFKB1NFKB2RELAMAPK1ALDH1A1 | |
| SCHEMBL30086083 | 0.78 | GRM2 (0.43) | MAPK1ALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL190124 | 0.78 | GRM2 (0.43) | MAPK1ALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL25755453 | 0.78 | ALDH1A1 (0.36) | NFKB1NFKB2RELAMAPK1ALDH1A1 | |
| SCHEMBL17479967 | 0.76 | ALDH1A1 (0.41) | ALDH1A1CYP1A2ALOX15MGAMGAA | |
| SCHEMBL26521044 | 0.76 | ALDH1A1 (0.41) | ALDH1A1CYP1A2ALOX15MGAMGAA | |
| SCHEMBL12868635 | 0.76 | ALDH1A1 (0.41) | ALDH1A1CYP1A2ALOX15MGAMGAA | |
| SCHEMBL32674026 | 0.76 | ALDH1A1 (0.41) | ALDH1A1CYP1A2ALOX15MGAMGAA | |
| SCHEMBL26529108 | 0.76 | ALDH1A1 (0.41) | ALDH1A1CYP1A2ALOX15MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105111155-B | A kind of synthetic method of 4,7- diaza spiro [2.5] octane -7- t-butyl formate | 武汉工程大学 | 2018-12-14 | — | — | CN | claimed |