Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11342173 | 1.00 | TSHR (0.38) | TSHRMCL1 | |
| SCHEMBL19999909 | 0.82 | MCL1 (0.35) | TSHRMCL1 | |
| SCHEMBL29229762 | 0.82 | TSHR (0.32) | TSHR | |
| SCHEMBL11440220 | 0.82 | MCL1 (0.34) | MCL1 | |
| SCHEMBL9244478 | 0.80 | MCL1 (0.33) | MCL1 | |
| SCHEMBL11389400 | 0.79 | ALDH1A1 (0.35) | TSHR | |
| SCHEMBL11389398 | 0.79 | ALDH1A1 (0.35) | TSHR | |
| SCHEMBL21848033 | 0.78 | TSHR (0.30) | TSHR | |
| SCHEMBL21848035 | 0.78 | TSHR (0.30) | TSHR | |
| SCHEMBL448049 | 0.78 | ADRA2A (0.41) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086927-B1 | IMINIUM SALTS AND METHODS OF PREPARING ELECTRON DEFICIENT OLEFINS USING SUCH NOVEL IMINIUM SALTS | LOCTITE R & D LTD (IE) | 2013-02-27 | — | — | EP | disclosed |
| US-8022251-B2 | Iminium salts and methods of preparing electron deficient olefins using such novel iminium salts | LOCTITE (R&D) LIMITED (IE) | 2011-09-20 | — | — | US | disclosed |
| US-8022251-B2 | Iminium salts and methods of preparing electron deficient olefins using such novel iminium salts | LOCTITE (R&D) LIMITED (IE) | 2011-09-20 | — | — | US | disclosed |
| US-20090203934-A1 | NOVEL IMINIUM SALTS AND METHODS OF PREPARING ELECTRON DEFICIENT OLEFINS USING SUCH NOVEL IMINIUM SALTS | LOCTITE (R&D) LIMITED (IE) | 2009-08-13 | — | — | US | disclosed |
| US-20090203934-A1 | NOVEL IMINIUM SALTS AND METHODS OF PREPARING ELECTRON DEFICIENT OLEFINS USING SUCH NOVEL IMINIUM SALTS | LOCTITE (R&D) LIMITED (IE) | 2009-08-13 | — | — | US | disclosed |
| WO-2008050313-A1 | IMINIUM SALTS AND METHODS OF PREPARING ELECTRON DEFICIENT OLEFINS USING SUCH NOVEL IMINIUM SALTS | LOCTITE (R & D) LIMITED (IE) | 2008-05-02 | — | — | WO | disclosed |
| EP-0001847-B1 | PROCESS FOR THE PREPARATION OF ALKENYL CYANOACETATES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1981-03-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203934-A1 | NOVEL IMINIUM SALTS AND METHODS OF PREPARING ELECTRON DEFICIENT OLEFINS USING SUCH NOVEL IMINIUM SALTS | IDH2, MACF1, LIG4 | TSHR 4881/4885MCL1 2684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.