Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | AGER | Q15109 | 3/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371438 | 0.83 | MEN1 (0.51) | KMT2AKDM4EMEN1NPC1MITF | |
| SCHEMBL11714853 | 0.83 | ALDH1A1 (0.49) | KMT2AKDM4EMEN1NPC1MITF | |
| SCHEMBL11671526 | 0.82 | KDM4E (0.50) | KMT2AKDM4EMEN1NPC1MITF | |
| SCHEMBL2346348 | 0.74 | ALDH1A1 (0.47) | KMT2AKDM4EMEN1NPC1MITF | |
| SCHEMBL3430597 | 0.74 | KDM4E (0.46) | KMT2AKDM4EMEN1NPC1MITF | |
| SCHEMBL2037132 | 0.74 | ALDH1A1 (0.51) | KMT2AKDM4EMEN1NPC1MITF | |
| SCHEMBL3586530 | 0.74 | ALDH1A1 (0.51) | KMT2AKDM4EMEN1NPC1MITF | |
| SCHEMBL9124783 | 0.72 | SMN1; SMN2 (0.49) | KMT2AKDM4EMEN1NPC1MITF | |
| SCHEMBL12088125 | 0.71 | ALDH1A1 (0.46) | KMT2AKDM4EMEN1NPC1MITF | |
| SCHEMBL5801159 | 0.71 | KDM4E (0.47) | KMT2AKDM4EMEN1NPC1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4248677-A | ELECTROCHEMICAL REDUCTION OF IMINES | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1981-02-03 | — | — | US | disclosed |