Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | MARK3 | P27448 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.38 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.38 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.38 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5463933 | 0.83 | ABCG2 (0.44) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL23715865 | 0.77 | RXRA (0.49) | RXRARXRBRXRGP2RX3CTSS | |
| SCHEMBL23974730 | 0.76 | CCNE2 (0.41) | RORCCCNE2CDK4CCND1CCNE1 | |
| SCHEMBL11720549 | 0.75 | TP53 (0.50) | RXRARXRBRXRGRORCTRPV1 | |
| SCHEMBL26245660 | 0.75 | RXRA (0.47) | RXRARXRBRXRGP2RX3CTSS | |
| SCHEMBL17805401 | 0.74 | TAS2R14 (0.48) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL23974261 | 0.73 | NOTUM (0.46) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL23974249 | 0.73 | CCNE2 (0.43) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL22621594 | 0.73 | RXRA (0.50) | RXRARXRBRXRGP2RX3CTSS | |
| SCHEMBL12002404 | 0.73 | RXRA (0.50) | RXRARXRBRXRGP2RX3CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257805-A | Herbicidal (4-substituted-phenylamino)-3-(trifluoromethyl)phenyl)ureas | SHELL OIL COMPANY (US) | 1981-03-24 | — | — | US | disclosed |