Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9350213 | 0.85 | ALDH1A3 (0.49) | RXRARXRBRXRGALDH1A3ALDH1A1 | |
| SCHEMBL16959421 | 0.84 | RXRA (0.46) | RXRARXRBRXRGALDH1A3CTSS | |
| SCHEMBL16952489 | 0.84 | RXRA (0.49) | RXRARXRBRXRGCTSSCTSK | |
| SCHEMBL14033967 | 0.81 | ALDH1A3 (0.52) | ALDH1A3ALDH1A1TSHRAOX1CYP1A2 | |
| SCHEMBL512997 | 0.81 | ALDH1A1 (0.61) | ALDH1A3ALDH1A1TSHRKIF11AOX1 | |
| SCHEMBL1713698 | 0.79 | ALDH1A1 (0.57) | ALDH1A3ALDH1A1TSHRAOX1AKR1C3 | |
| SCHEMBL26245660 | 0.78 | RXRA (0.47) | RXRARXRBRXRGALDH1A3CTSS | |
| SCHEMBL11344348 | 0.77 | RXRA (0.46) | RXRARXRBRXRGALDH1A1TSHR | |
| SCHEMBL14090077 | 0.77 | S1PR3 (0.44) | RXRARXRBRXRGALDH1A3ALDH1A1 | |
| SCHEMBL16403516 | 0.77 | KIF11 (0.35) | RXRARXRBRXRGALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |