Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.63 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15058859 | 0.84 | CYP19A1 (0.81) | CYP19A1CDK5CDK5R1AKT1CHEK1 | |
| SCHEMBL693721 | 0.82 | CYP19A1 (0.61) | CYP19A1CDK5CDK5R1AKT1HDAC6 | |
| SCHEMBL15073406 | 0.79 | CYP19A1 (0.72) | CYP19A1CDK5CDK5R1KDM4EMEN1 | |
| SCHEMBL11556289 | 0.78 | CYP19A1 (1.00) | CYP19A1CDK5CDK5R1F2PPARG | |
| SCHEMBL693207 | 0.78 | CYP19A1 (0.52) | CYP19A1CDK5CDK5R1AKT1HDAC6 | |
| SCHEMBL11348242 | 0.77 | NPC1 (0.63) | CYP19A1F2PPARGCASP3SENP8 | |
| SCHEMBL11317629 | 0.77 | CYP19A1 (0.74) | CYP19A1CDK5CDK5R1CHEK1KDM4E | |
| SCHEMBL11334561 | 0.76 | RHEB (0.56) | HDAC6KDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL4877838 | 0.76 | CYP19A1 (0.63) | CYP19A1CDK5CDK5R1AKT1CASP3 | |
| SCHEMBL11339106 | 0.76 | CHEK2 (0.48) | CYP19A1HDAC6FFAR1F2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4308194-A | Heterocyclic benzoate ultraviolet stabilizers and their use in organic compositions | EASTMAN KODAK COMPANY (US) | 1981-12-29 | — | — | US | disclosed |
| US-4075220-A | FOR POLYMERS | EASTMAN KODAK COMPANY (US) | 1978-02-21 | — | — | US | disclosed |
| US-4065427-A | Polychromophoric heterocyclic ultraviolet stabilizers and their use in organic compositions | EASTMAN KODAK COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4000148-A | POLYMERS | EASTMAN KODAK COMPANY (US) | 1976-12-28 | — | — | US | disclosed |
| US-3957813-A | BENZOXAZOLYL PHENYL AROMATIC ESTER COMPOUNDS AND THEIR USE AS ULTRAVIOLET STABILIZERS IN ORGANIC COMPOSITIONS | EASTMAN KODAK COMPANY (US) | 1976-05-18 | — | — | US | disclosed |