Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.72 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.50 |
| ▸ | ITK | Q08881 | 3/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16382899 | 0.91 | CYP19A1 (0.63) | CYP19A1CDK5CDK5R1ITKGSK3B | |
| SCHEMBL15058859 | 0.90 | CYP19A1 (0.81) | CYP19A1CDK5CDK5R1ITKGSK3B | |
| SCHEMBL11556289 | 0.84 | CYP19A1 (1.00) | CYP19A1CDK5CDK5R1ITKALDH1A1 | |
| SCHEMBL11317629 | 0.83 | CYP19A1 (0.74) | CYP19A1CDK5CDK5R1ITKALDH1A1 | |
| SCHEMBL16382914 | 0.81 | RAB9A (0.63) | CYP19A1ITKALDH1A1MEN1HPGD | |
| SCHEMBL29651657 | 0.80 | CYP19A1 (0.61) | CYP19A1CDK5CDK5R1ITKGSK3B | |
| SCHEMBL10671177 | 0.80 | CYP19A1 (0.61) | CYP19A1CDK5CDK5R1ITKGSK3B | |
| SCHEMBL6987662 | 0.80 | HPGD (0.71) | CYP19A1ALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL11344486 | 0.79 | CYP19A1 (0.63) | CYP19A1CDK5CDK5R1ITKALDH1A1 | |
| SCHEMBL4877838 | 0.79 | CYP19A1 (0.63) | CYP19A1CDK5CDK5R1ITKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115052860-B | Collagen 1 translation inhibitors and methods of use thereof | 艾尼莫生物科技公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-115052860-A | Collagen 1 translation inhibitors and methods of use thereof | 艾尼莫生物科技公司 | 2022-09-13 | — | — | CN | disclosed |
| WO-2013095304-A1 | PROCESSES FOR PREPARING INDOLES | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2013-06-27 | — | — | WO | disclosed |