Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11339568 | 0.85 | OPRM1 (0.44) | OPRM1SIGMAR1SLC22A1NR1I2ABCB1 | |
| SCHEMBL11334216 | 0.85 | OPRM1 (0.44) | OPRM1SIGMAR1SLC22A1NR1I2ABCB1 | |
| SCHEMBL11331578 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KDM4EMEN1NPC1MITF | |
| SCHEMBL11481377 | 0.78 | ALDH1A1 (0.37) | ALDH1A1KDM4EMEN1NPC1MITF | |
| SCHEMBL11456889 | 0.76 | OPRM1 (0.45) | OPRM1SIGMAR1SLC22A1NR1I2ABCB1 | |
| SCHEMBL11344631 | 0.74 | MEN1 (0.36) | ALDH1A1MEN1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL11338281 | 0.74 | ALDH1A1 (0.40) | ALDH1A1KDM4EMEN1NPC1MITF | |
| SCHEMBL11447557 | 0.72 | OPRM1 (0.50) | ALDH1A1KDM4EMEN1NPC1MITF | |
| SCHEMBL11347005 | 0.72 | OPRM1 (0.47) | ALDH1A1KDM4EMEN1NPC1MITF | |
| SCHEMBL11344671 | 0.71 | ALDH1A1 (0.36) | ALDH1A1KDM4EMEN1NPC1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE30837-E | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1981-12-29 | — | — | US | disclosed |
| US-4199589-A | N-(2-Aminocycloheptyl)acylanilides and methods to treat depression | SZMUSZKOVICZ JACOB (US) | 1980-04-22 | — | — | US | disclosed |
| US-4172898-A | N-(2-aminocycloheptyl)acylanilides | THE UPJOHN COMPANY (US) | 1979-10-30 | — | — | US | disclosed |
| US-4169156-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-09-25 | — | — | US | disclosed |
| US-4159339-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-06-26 | — | — | US | disclosed |