Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.30 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.30 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11334220 | 0.84 | MEN1 (0.44) | MEN1KMT2ASIGMAR1CHRM2CHRM3 | |
| SCHEMBL11456891 | 0.80 | MEN1 (0.42) | MEN1KMT2ASIGMAR1CHRM2CHRM3 | |
| SCHEMBL11331580 | 0.76 | SIGMAR1 (0.41) | MEN1KMT2ASIGMAR1LMNASMN1; SMN2 | |
| SCHEMBL11481378 | 0.75 | MEN1 (0.39) | MEN1KMT2ASIGMAR1LMNACHRM2 | |
| SCHEMBL11338282 | 0.75 | MEN1 (0.36) | MEN1KMT2ASIGMAR1LMNASMN1; SMN2 | |
| SCHEMBL11344628 | 0.74 | ALDH1A1 (0.33) | MEN1KMT2ASIGMAR1LMNASMN1; SMN2 | |
| SCHEMBL11446906 | 0.72 | SIGMAR1 (0.39) | MEN1KMT2ASIGMAR1LMNASMN1; SMN2 | |
| SCHEMBL11347007 | 0.71 | SIGMAR1 (0.43) | MEN1KMT2ASIGMAR1SMN1; SMN2POLB | |
| SCHEMBL11465431 | 0.71 | HPGD (0.39) | MEN1KMT2ASIGMAR1LMNACHRM2 | |
| SCHEMBL11446572 | 0.70 | MEN1 (0.34) | MEN1KMT2ASIGMAR1SMN1; SMN2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE30837-E | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1981-12-29 | — | — | US | disclosed |
| US-4199589-A | N-(2-Aminocycloheptyl)acylanilides and methods to treat depression | SZMUSZKOVICZ JACOB (US) | 1980-04-22 | — | — | US | disclosed |
| US-4172898-A | N-(2-aminocycloheptyl)acylanilides | THE UPJOHN COMPANY (US) | 1979-10-30 | — | — | US | disclosed |
| US-4169156-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-09-25 | — | — | US | disclosed |
| US-4159339-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-06-26 | — | — | US | disclosed |