Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22966418 | 1.00 | KMO (0.49) | KMOHDAC4HDAC2HDAC8CYP11B2 | |
| SCHEMBL26672083 | 0.91 | MAPK1 (0.40) | KMOHDAC4HDAC2HDAC8MAPK1 | |
| SCHEMBL26936966 | 0.81 | KMO (0.53) | KMOHDAC4HDAC2HDAC8CYP11B2 | |
| SCHEMBL2769234 | 0.79 | CYP3A4 (0.44) | HDAC8ACMSDMAPK1TDP1SLC18A3 | |
| SCHEMBL669730 | 0.78 | KMO (0.64) | KMOHDAC4HDAC2HDAC8CYP11B2 | |
| SCHEMBL5667650 | 0.78 | KMO (0.64) | KMOHDAC4HDAC2HDAC8CYP11B2 | |
| SCHEMBL4055904 | 0.77 | CYP3A4 (0.45) | HDAC8ACMSDMAPK1TDP1EPHX2 | |
| SCHEMBL5666805 | 0.75 | KMO (0.62) | KMOHDAC4HDAC2HDAC8CYP11B2 | |
| SCHEMBL778529 | 0.75 | HDAC4 (0.63) | KMOHDAC4HDAC2HDAC8CYP11B2 | |
| Hydrogen Peroxide SCHEMBL11391460 | 0.73 | KMO (0.71) | KMOHDAC4HDAC2HDAC8CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0011790-B1 | PROCESS FOR THE PREPARATION OF NITRODIPHENYL AMINE DERIVATIVES | BAYER AG (DE) | 1981-07-15 | — | — | EP | disclosed |
| US-4238407-A | Process for the preparation of nitro diphenyl amine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-09 | — | — | US | disclosed |
| EP-0011790-A1 | Process for the preparation of nitrodiphenyl amine derivatives | BAYER AG (DE) | 1980-06-11 | — | — | EP | disclosed |