SCHEMBL2769234

SCHEMBL2769234

O=C=Nc1ccc(C2CCCCC2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 1/20 0.44
▸ TSHR P16473 1/20 0.44
▸ NOS3 P29474 2/20 0.43
▸ NOS1 P29475 2/20 0.43
▸ NOS2 P35228 2/20 0.43
▸ HTT P42858 2/20 0.41
▸ LMNA P02545 1/20 0.41
▸ GAA P10253 2/20 0.41
▸ MAPT P10636 2/20 0.41
▸ HDAC8 Q9BY41 2/20 0.41
▸ HDAC6 Q9UBN7 2/20 0.41
▸ HDAC1 Q13547 1/20 0.41
▸ RAB9A P51151 1/20 0.41
▸ TDP1 Q9NUW8 3/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ HSP90AA1 P07900 1/20 0.40
▸ EPHX2 P34913 1/20 0.39
▸ HAO1 Q9UJM8 1/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.38
▸ KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4055904 0.98 CYP3A4 (0.45) CYP3A4TSHRNOS3NOS1NOS2
SCHEMBL16345263 0.90 CYP3A4 (0.48) CYP3A4TSHRNOS3NOS1NOS2
Cyclohexane SCHEMBL1006843 0.81 CYP3A4 (0.61) CYP3A4TSHRTDP1EPHX2MAPK1
SCHEMBL3965544 0.81 P2RY6 (0.44) NOS3NOS1NOS2HTTLMNA
SCHEMBL9351603 0.80 CYP3A4 (0.40) CYP3A4TSHRRAB9ATDP1MAPK1
SCHEMBL11344825 0.79 KMO (0.49) CYP3A4HTTLMNAMAPTHDAC8
SCHEMBL22966418 0.79 KMO (0.49) CYP3A4HTTLMNAMAPTHDAC8
SCHEMBL18553011 0.77 NOTUM (0.41) NOS3NOS1NOS2HTTLMNA
SCHEMBL15260520 0.76 HDAC8 (0.52) HTTLMNAGAAMAPTHDAC8
SCHEMBL6275125 0.76 HDAC8 (0.52) HTTLMNAGAAMAPTHDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12509547-B2 Synthesis of linear polyoxazolidinones using uretdiones as diisocyanate component BASF SE (DE) 2025-12-30 — — US claimed
US-20230348657-A1 SYNTHESIS OF LINEAR POLYOXAZOLIDINONES USING URETDIONES AS DIISOCYANATE COMPONENT BASF SE (DE) 2023-11-02 — — US claimed
EP-4185626-A1 SYNTHESIS OF LINEAR POLYOXAZOLIDINONES USING URETDIONES AS DIISOCYANATE COMPONENT BASF SE (DE) 2023-05-31 — — EP claimed
CN-112996835-B Method for producing thermoplastic polyoxazolidone polymers 科思创知识产权两合公司 2022-12-13 — — CN claimed
US-11427671-B2 Method for the production of thermoplastic polyoxazolidinone polymers COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2022-08-30 — — US claimed
EP-3873961-B1 METHOD FOR THE PRODUCTION OF THERMOPLASTIC POLYOXAZOLIDINONE POLYMERS COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2022-08-17 — — EP claimed
US-11370874-B2 Method for the production of thermoplastic polyoxazolidone polymers COVESTRO DEUTSCHLAND AG (DE) 2022-06-28 — — US claimed
EP-3681924-B1 METHOD FOR THE PRODUCTION OF THERMOPLASTIC POLYOXAZOLIDINONE POLYMERS COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2022-05-18 — — EP claimed
EP-3873962-B1 METHOD FOR THE PRODUCTION OF THERMOPLASTIC POLYOXAZOLIDINONE POLYMERS COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2022-05-18 — — EP claimed
US-11326018-B2 Process for the synthesis of polyoxazolidinone compounds COVESTRO DEUTSCHLAND AG (DE) 2022-05-10 — — US claimed
EP-3456753-A1 METHOD FOR THE PRODUCTION OF THERMPLASTIC POLYOXAZOLIDINONE POLYMERS Covestro Deutschland AG (DE) 2019-03-20 — — EP claimed
WO-2018141743-A1 METHOD FOR THE PRODUCTION OF POLYOXAZOLIDINONE POLYMER COMPOUNDS COVESTRO DEUTSCHLAND AG (DE) 2018-08-09 — — WO claimed
EP-3357949-A1 METHOD FOR THE PRODUCTION OF POLYOXAZOLIDINONE POLYMER COMPOUNDS Covestro Deutschland AG (DE) 2018-08-08 — — EP claimed
US-10040808-B2 Silane-modified formamides COVESTRO DEUTSCHLAND AG (DE) 2018-08-07 — — US claimed
WO-2018033562-A1 PROCESS FOR THE SYNTHESIS OF POLYOXAZOLIDINONE COMPOUNDS COVESTRO DEUTSCHLAND AG (DE) 2018-02-22 — — WO claimed
US-20180022871-A1 PROCESS FOR THE SYNTHESIS OF POLYOXAZOLIDINONE COMPOUNDS WITH HIGH STABILITY COVESTRO DEUTSCHLAND AG (DE) 2018-01-25 — — US claimed
EP-3256508-A1 PROCESS FOR THE SYNTHESIS OF POLYOXAZOLIDINONE COMPOUNDS WITH HIGH STABILITY Covestro Deutschland AG (DE) 2017-12-20 — — EP claimed
CN-107207700-A Method for synthesizing polyoxazolidone compound with high stability 科思创德国股份有限公司 2017-09-26 — — CN claimed
WO-2016128380-A1 PROCESS FOR THE SYNTHESIS OF POLYOXAZOLIDINONE COMPOUNDS WITH HIGH STABILITY COVESTRO DEUTSCHLAND AG (DE) 2016-08-18 — — WO claimed
US-4918148-A IMPROVED FLOWABILITY, MOLD RELEASE AND-OR NOTCHED IMPACT STRENGTH BAYER AKTIENGESELLSCHAFT (DE) 1990-04-17 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509547-B2 Synthesis of linear polyoxazolidinones using uretdiones as diisocyanate component BMP1, BMP4, PBRM1 CYP3A4 1801/4885TSHR 4875/4885NOS3 1036/4885
US-10040808-B2 Silane-modified formamides PFAS, ITGA8, CAD CYP3A4 3614/4885TSHR 4875/4885NOS3 2699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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